ARVs DRUG CLASSES

ARVs DRUG CLASSES Here are detailed notes on ARV drug classes, their side effects, and Differentiated Service Delivery (DSD) models for treatment and care: ARV Drugs: Classes and Side Effects Antiretroviral (ARV) drugs are used to manage HIV/AIDS by reducing the viral load and preventing disease progression. They are classified into several classes based on their mechanism of action. Classes of ARV Drugs Nucleoside Reverse Transcriptase Inhibitors (NRTIs): Examples: Zidovudine (AZT), Lamivudine (3TC), Tenofovir (TDF), Emtricitabine (FTC). Mechanism: Inhibits reverse transcriptase by incorporating faulty nucleotides, halting viral replication. Side Effects: Anemia, lactic acidosis, lipodystrophy, nephrotoxicity (e.g., TDF), nausea, and headache. Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs): Examples: Efavirenz (EFV), Nevirapine (NVP), Etravirine (ETR). Mechanism: Binds directly to reverse transcriptase, causing conformational changes that prevent its a...