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Showing posts from February, 2024

CHOKING FIRST AID

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CHOKING   The management of choking involves a set of immediate actions to assist a person who is unable to breathe due to a blocked airway. Here are the steps for managing choking in adults and children: Assess the Situation: Quickly assess the person's ability to breathe and speak. If the person is unable to breathe, cough, or speak, immediate action is needed. Encourage Coughing: If the person is still conscious and can cough, encourage them to cough forcefully to try and dislodge the object. Perform Abdominal Thrusts (Heimlich Maneuver): Stand behind the person and place your arms around their waist. Make a fist with one hand and place the thumb side against the middle of the person's abdomen, just above the navel. Grasp the fist with your other hand and give quick, upward thrusts to help force the object out. If the person is pregnant or obese, chest thrusts may be used instead. Back Blows: If abdominal thrusts do not work, or if the person is pregnant or obese, give back

DIAPEDESIS & IMMUNE RESPONSE

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 DIAPEDESIS Diapedesis, also known as transmigration, is a crucial step in the immune response where white blood cells (leukocytes) exit the bloodstream and move towards sites of infection, inflammation, or tissue damage. This process is part of the overall sequence of events that allows immune cells to reach the affected tissues where they can carry out their protective functions. Diapedesis involves the migration of leukocytes through the walls of blood vessels. Here are key points about diapedesis: Initiation: Diapedesis is typically initiated in response to signals from the site of infection or tissue damage. These signals include chemical cues such as chemokines. Adhesion to Endothelial Cells: White blood cells, particularly neutrophils, adhere to the endothelial cells lining the blood vessels at the site of inflammation. Adhesion is facilitated by interactions between adhesion molecules on the surface of both the white blood cells and the endothelial cells. Rolling: Before diaped

MARGINATION AND IMMUNE RESPONSE

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  MARGINATION Margination refers to the process in which white blood cells (leukocytes) move to the periphery, or margins, of blood vessels during inflammation. This phenomenon is a crucial step in the immune response, particularly in the context of an inflammatory reaction or an immune system response to infection or injury. Margination is part of the sequence of events that allows immune cells to efficiently exit the bloodstream and reach the site of infection or tissue damage. Here are key points about margination: Inflammatory Response: Margination is a step in the inflammatory response, which is the body's natural reaction to injury or infection. During inflammation, various signals, including chemical signals (chemokines), are released at the site of injury or infection. White Blood Cell Recruitment: White blood cells, or leukocytes, play a crucial role in the immune response. To combat infections or injuries, these cells need to leave the bloodstream and reach the affected t